Biography
I am a diligent Doctor of Veterinary Medicine and Biotechnology Master's graduate, currently serving as the Managing Director of Bioengineering Research and Development (Private) Limited. With over two years of experience, I specialize in cell culture studies, molecular and microbiological assays, and biomaterials research. My expertise includes conducting a variety of assays such as WST-8, collagen release, ALP, disc diffusion, and turbidimetric bacterial analysis. Additionally, I have gained expertise in in-vivo mice model studies, immunohistochemistry, and histological studies. I have a proven track record of contributing to innovative projects in 3D bioprinting, electrophoretic deposition, and hydrogel synthesis, with publications in reputable scientific journals. Equipped with strong analytical skills and effective communication, I am dedicated to advancing cutting-edge research in multidisciplinary environments.
Research Interests
My research interests focus on the intersection of biofabrication and regenerative medicine, specifically the development of patient-specific 3D-printed scaffolds and bio-inks (e.g., alginate, guar gum, and PEEK) for complex skin regeneration, burn care, and cartilage repair. I specialize in engineering multifunctional surface coatings and hydrogels that incorporate therapeutic ions, exosomes, and natural bioactive agents to provide sustained antimicrobial efficacy and enhanced osseointegration for orthopedic implants. Furthermore, I am dedicated to advancing translational research through comprehensive biological profiling, including in-vivo mice models and CAM assays, to validate the angiogenic and healing potential of innovative biomaterials for clinical applications.
Areas of Expertise
1. Biofabrication and Advanced Manufacturing
3D Bioprinting and DIW: Expert in Direct Ink Writing (DIW) for fabricating patient-specific scaffolds using advanced polymers like PEEK, Guar gum, and Alginate.
Electrospinning and Hybrid Systems: Specialized in developing electrospun fibrous patches and integrating them with bioprinting to create multi-layered tissue constructs.
Bio-ink Formulation: Advanced knowledge in synthesizing and characterizing novel bio-inks (e.g., OGG, ALG/PVA) reinforced with bioactive glass nanoparticles for wound healing and bone repair.
Surface Engineering: Proficient in Electrophoretic Deposition (EPD) for applying bioactive, antimicrobial, and corrosion-resistant coatings (Chitosan, Xanthan, Hydroxyapatite) onto surgical-grade implants.
2. Tissue Engineering and Regenerative Medicine
Wound Care and Skin Regeneration: Designing biomimetic scaffolds loaded with therapeutic agents (Lawsone, Cu-Ag nanoparticles) specifically for burn care and skin tissue engineering.
Orthopedic and Dental Applications: Developing composite coatings and scaffolds for bone and cartilage repair, focusing on enhancing osseointegration and mechanical properties.
Advanced Biological Profiling: Extensive experience in in-vitro assays (cell culture, angiogenesis/CAM assays) and in-vivo mice models to validate the safety and therapeutic efficacy of biomaterials.
3. Business Development and Management
Strategic Project Oversight: Managing the full lifecycle of high-impact research projects, including the World Bank-funded skin graft project, from conceptualization to animal trials and DRAP regulatory compliance.
Revenue Avenue Expansion: Driving growth through the commercialization of specialized fabrication equipment, including custom 3D bioprinters and electrospinning units.
Brand Launch and Portfolio Management: Strategically positioning and launching sub-brands such as Leafzee and Biorays to diversify company presence in the bioengineering market.
Academic-Industrial Liaison: Bridging the gap between lab-scale research and commercial prototypes, evidenced by multiple international publications and award-winning posters.
4. Veterinary Science and Biotechnology (Interdisciplinary)
Clinical Veterinary Medicine: Specialized background as a Doctor of Veterinary Medicine (DVM) with expertise in biomarker studies and immunohistochemistry.
Microbiological Analysis: Skilled in conducting disc diffusion, turbidimetric bacterial analysis, and developing antimicrobial coatings derived from natural sources.
Member Details
Education
Master of Science in Biotechnology (2022–2024): Completed at the National University of Medical Sciences, Rawalpindi, Pakistan, with a CGPA of 3.31/4.00. My thesis focused on the Development of 3D printed scaffolds loaded with bioactive glass for potential burn care applications.
Doctor of Veterinary Medicine (2016–2020): Earned from Gomal University, Dera Ismail Khan, Pakistan, achieving a CGPA of 3.28/4.00.
Higher Secondary School Certificate (2013–2015): Completed in the Pre-medical field through the Federal Board of Intermediate and Secondary Education (FBISE), Islamabad, with a Grade B.
Secondary School Certificate (2011–2013): Obtained in Science from the Board of Intermediate and Secondary Education (BISE), Sargodha, with a Grade A+.
Responsibilities
Strategic Research Leadership: Directing the Research and Development department by overseeing multidisciplinary projects in 3D bioprinting, electrophoretic deposition, and hydrogel synthesis for tissue engineering and oncological applications.
Advanced Biofabrication Oversight: Leading the development of innovative biomaterials, including bio-inks (OGG/ALG) and electrospun patches, validated through both in-vitro assays and in-vivo mice or CAM models.
Business Development and Revenue Expansion: Driving company growth by identifying new revenue streams, specifically through the commercialization of specialized fabrication equipment such as custom-designed 3D bioprinters and electrospinning units.
Brand Strategy and Portfolio Management: Managing the launch and market positioning of sub-brands, including Leafzee and Biorays, to diversify the company’s presence in the biomedical and bioengineering sectors.
Grant and Project Management: Serving as Project Director for high-value initiatives, such as the World Bank-funded skin graft project, while overseeing the entire lifecycle from animal trials to DRAP regulatory filings and intellectual property protection.
Scientific Communication: Supervising the compilation of research findings for publication in prestigious international journals and representing the company’s innovations at global conferences.
Current Projects
1. Development of biopolymeric scaffolds loaded with ion doped mesoporous bioactive glass for Potential Burn Care Applications
2. Fagonia Indica loaded magnetic particles for oncological applications
3. Exosome loaded biopolymeric gels for potential wound care applications
4. Development and characterization of chondro-integrative gel for cartilage repair
5. Carvacol loaded kaolin coatings on surgical grade stainless steel for orthopedic application: detailed in-vitro material and biological characterization
6. Electrospun Polyvinyl Alcohol and Alginate Dialdehyde-Gelatin Patches: A Cost-Effective Approach for Burn Wound Care with Prolonged Antimicrobial Efficacy
7. Extended Biological Profiling of Xanthan Dialdehyde Based Composite Coatings for Orthopedic Implants
8. Direct Ink Write 3D Printed Poly (ethylene oxide)/ Guar Gum/ lawsone Scaffolds for Burn Care Applications
9. Choline chloride bio-ionic liquid cross-linked alginate: Effect of bio-ionic liquid ratio on biocompatibility, angiogenesis and antibacterial potential
10. Biocompatible tragacanth Gum/polyvinylpyrrolidone-based 3D scaffold enriched with lawsone fabrication and in-vitro characterizations for potential wound healing applications
11. Development and characterization of drug free bioactive glass nanoparticles for biomedical applications
12. Development and commercialization low cost patient specific skin grafts
Publications
Propolis enhanced sodium alginate hydrogel enriched with copper doped mesoporous bioactive glass nanoparticles for advanced burn care applications
Chronic wounds, with prolonged healing time, remain a formidable challenge due to lack of angiogenesis, antimicrobial effect, and biocompatibility of conventional wound dressings. The current study focuses on developing novel copper-doped mesoporous ...
Chitosan/mesoporous bioactive glass nanoparticles (MBGNs) composite coating deposited on silk suture: An initial in-vivo study
This is imperative to inhibit suture related postoperative infections, which hinder and delay the healing process. Thus, there is a pressing need to modify the surface of the suture that facilitates the healing process. Herein, we synthesized mesopor ...
Development of therapeutic ions loaded oxidized guar gum and sodium alginate-based 3D printed biomimetic scaffolds investigated in-vitro and in-vivo for burn wound repair
A novel, potentially effective, and precise 3D-printed scaffold was fabricated for presumable burn injuries. A natural polysaccharide guar gum (GG) was chemically modified (oxidized) to guar gum dialdehyde (OGG) to enhance its reactivity towards the ...
Effect of chitosan based composite coating on silk suture to enhance the wound healing ability: An initial in-vivo study
This is imperative to inhibit suture related postoperative infections, which hinder and delay the healing process. Thus, there is a pressing need to modify the surface of the suture that facilitates the healing process. Herein, we synthesized mesopor ...
Direct ink write 3D printed poly (ethylene oxide)/ Guar gum/ lawsone scaffolds for burn care applications
Burn is one of the leading causes of trauma worldwide, with significantly higher mortality rates in third-world countries. Therefore, there is an urgent need to provide dynamic solutions to treat burns, particularly for third-degree burn patients. Th ...
Re In-vitro evaluation of tragacanth gum based 3D scaffold enriched with lawsone: A potential approach for wound repair
In the realm of soft tissue engineering and wound dressings, biomaterials-based three-dimensional (3D) biocompatible scaffolds emerged as a promising candidate. Herein, a novel combination of tragacanth gum (TG) combined with polyvinylpyrrolidone (PV ...
Development and characterization of glutaryl thiourea crosslinked novel hydrogel; a detailed analysis of biocompatibility, angiogenesis, and antibacterial potential
In this study, we successfully synthesized four novel chitosan hydrogels by carefully crosslinking them with varying concentrations of glutaryl di-isothiocyanate (GTU). This thoughtful approach not only imparts a subtle yellowish tint to the polymer ...
Microstructure, wear, and corrosion properties of PEEK-based composite coating incorporating titania- and copper-doped mesoporous bioactive glass nanoparticles
Poor wear- and corrosion-resistance of 316L SS implants are critical problems in orthopedic implants. This study aims to improve the wear- and corrosion-resistance of 316L SS through surface coating. In this study, a bilayer composite coating consist ...
Fabrication and in vitro insights of polyethylene oxide/locust bean gum enriched with ethanolic extract ginger-based 3D printed scaffold
Herein, this study unveils a novel ink blend merging polyethylene oxide (PEO) and locust bean gum (LBG) enriched with ethanolic extract of ginger (GR), revolutionizing the development of an essential network of 3D scaffold. The ink blend was diligent ...
Lawsone-loaded PVA/alginate dialdehyde-gelatin electrospun fibers for wound healing: development and characterization
The need for tissue-engineered mats for soft tissue repair regeneration is rising due to increasing numbers of traumatic injuries. In this study, novel, biocompatible electrospun mat based on polyvinyl alcohol (PVA) and alginate dialdehyde-gelatin (A ...
Development and characterization of polyethylene oxide and guar gum-based hydrogel; a detailed in-vitro analysis of degradation and drug release kinetics
Herein, we synthesized hydrogel films from crosslinked polyethylene oxide (PEO) and guar gum (GG) which can offer hydrophilicity, antibacterial efficacy, and neovascularization. This study focuses on synthesis and material/biological characterization ...
Development of hybrid polyvinylpyrrolidone/carboxymethyl cellulose/collagen incorporated oregano scaffolds via direct ink write printing for potential wound healing applications
Additive manufacturing can develop regenerative scaffolds for wound healing. 3D printing offers meticulous porosity, mechanical integrity, cell adhesion and cost-effectiveness. Herein, we prepared ink composed of carboxymethyl cellulose (CMC), polyvi ...
Synthesis and characterization of aloe vera and hyaluronic acid-infused agar-agar/ gelatin-based biopolymeric gel for potential skincare applications
The demand for bioactive and biodegradable skincare products is growing with rising skin complications despite bare cosmetics, pharmaceuticals, and nutraceuticals. Biocompatible, Agar-agar (AA) and gelatin (G) based biopolymeric gel infused with hyal ...
3D-printed polyether-ether ketone/carboxymethyl cellulose scaffolds coated with Zn–Mn doped mesoporous bioactive glass nanoparticles
Patient-specific fabrication of scaffold/implant requires an engineering approach to manufacture the ideal scaffold. Herein, we design and 3D print scaffolds comprised of polyether-ether-ketone (PEEK) and sodium-carboxymethyl cellulose (Na-CMC). The ...
Electrophoretic deposition of moringa loaded chitosan coatings on Mg: A study on antibacterial properties and degradation kinetics
Moringa loaded chitosan coatings (coating thickness ∼10 µm) were deposited on Mg substrate via electrophoretic deposition (applied electric field = 15 V/cm and deposition time = 20 min). Scanning electron microscopy images of chitosan/moringa coat ...
Advancing cartilage Repair: A Biomimetic approach with oxidized guar gum, chitosan, polyether ether ketone-based injectable hydrogel
Herein, we developed hydrogel (potentially injectable) composed of oxidized guar gum, chitosan, and polyether ether ketone to provide cartilage support and regeneration. Scanning electron microscopy confirmed spongy and microporous structures. The sy ...
Rosemary loaded Xanthan coatings on surgical grade stainless steel for potential orthopedic applications
The demand for orthopedic implants coated with biocompatible and bactericidal materials is escalating because of the rising bacterial resistance against synthetic antibiotics. Consequently, a non-toxic polysaccharide infused with the natural herb, i. ...
3D Printing Assisted Fabrication of Copper–Silver Mesoporous Bioactive Glass Nanoparticles Reinforced Sodium Alginate/Poly(vinyl alcohol) Based Composite Scaffolds: Designed for Skin Tissue Engineering
Additive manufacturing (also known as 3D printing) is a promising method for producing patient-specific implants. In the present study, sodium alginate (Na-ALG)/poly(vinyl alcohol) (PVA) polymer blends of varying ratios (1:0, 3:1, 1:1, and 1:3) were ...
A study on the effect of bioactive glass and hydroxyapatite-loaded Xanthan dialdehyde-based composite coatings for potential orthopedic applications
The most important challenge faced in designing orthopedic devices is to control the leaching of ions from the substrate material, and to prevent biofilm formation. Accordingly, the surgical grade stainless steel (316L SS) was electrophoretically dep ...